KUCTC Available Technologies

The University of Kansas Center for Technology Commercialization is pleased to offer visitors a new way to view KU technologies available for license, through the iBridge™ Web-based application.

The iBridge™ web-based application provides an additional way to view KU technologies available for license. Descriptions of KU technologies are accessible both through iBridge and the categorical links below.

The Kauffman Innovation Network, an initiative launched by the Ewing Marion Kauffman Foundation, is piloting the iBridge™ application in the U.S. by licensing several universities' technology transfer offices to post research findings. KU was part of the pilot program.

• Adaptive interface evaluator
  Interface between adaptive switch and sources of stimulation for children and adults who have little or no reliable communicative behavior.
• Alkaline-doped mercury cuprate superconductors
  Alkaline-doped superconductors of the formula X M.sub.2 Ca.sub.2 Cu.sub.3 O.sub.8+.alpha. are provided where X is selected from the group consisting of TI, Pb, Mo,Hg and mixtures thereof.
• Animal model for ovarian cancer cell line
  Ten (10) clonal lines from mouse ovarian surface epithelium of C57B6 mice.
• Anti-angiogenic properties of heparine-binding polycationic compaounds
  High-throughput screen that enables the rapid identification of heparin-binding compounds, and quantitative measurements of their binding affinity to heparin.
• Antibodies to mouse interferon gamma receptor
  These antibodies have been cataloged with respect to their subclasses, specificities, and relative binding avidities.
• Biologically active agents encapsulated in biodegradable starch/polymer matrices
  This formulation uses native, denatured starch and synthetic, biocompatible polymers to protect the active agent by encapsulating it.
• Bone-inducing agent
  A bone-inducing agent in extracts of Saos-2 cells that has been used to promote healing of large, surgically-induced bone defects.
• CasR-/Gcm2-Deficient mouse model
  The mouse model developed here was created from intercrossing CasR- and Gcm2-deficient mice in order to understand the role of the calcium-sensing receptor (CasR) in the skeleton.
• ChatTrack: Archiving and searching chat and instant messages
  ChatTrack archives and indexes the contents of instant messaging and chat room discussions in XML format.
• Compounds that inhibit testis specific soluble adenylyl cyclase (sAC)
  Reversible male contraceptive.
• Descripto
  The invention is a software package used to analyze complex polymer mixtures based on structural information only.
• Fabrication of porous ceramic films
  The invention is a new process that is used to generate pores in ceramic films, such as the ceramic high temperature superconductor films.
• FRAANK (Financial Reporting and Auditing Agent with Net Knowledge
  FRAANK-XBRL is intelligent agent software for accounting and auditing domain. It reads financial reports (e.g., 10K and 10Q) filed with the SEC.
• Fractionation of chromosomes using an affinity-based magnetic bead separation
  Fractionation of chromosomes using an affinity-based magnetic bead separation.
• GEMINI (Geo-Engineering Modeling through Internet Informatics)
  GEMINI is designed to provide programs to quantitatively analyze and model petroleum reservoirs without cost to the user. GEMINI allows operators to assemble and analyze on-line data.
• Gene knockout mouse model lacking follicle stimulating hormone beta gene
  Use of embryonic stem cells to delete the gene encoding the follicle stimulating hormone beta subunit gene.
• Generation of anti-methionine sulfoxide antibodies using plant methionine-rich protein
  The development of antibodies that can recognize MetO residues in proteins as a tool for the identifying of proteins targeted for methionine oxidation in vivo.
• Geodiscovery: An index of geographic information system (GIS) web mapping services
  Geodiscovery is an indexing service for ArcIMS map services.
• Geometric methods for analysis, design and optimization of fiber paths in two-based composites, and system thereof
  Steered fiber architecture may improve structural efficiency by tailoring local fiber orientation to the local internal load path.
• Headstrong: A CD-ROM program for helping children manage headaches
  A standalone CD-ROM program targeted at children ages 7-12 (the most common age range for the onset of disabling recurrent headaches).
• HDTV: Wideband planar antenna
  This technology provides for improvement of existing antennas. It improves the reception of digital TV broadcasts, especially in distant fringe areas or locations without a clear path to a transmitter.
• High resolution optical spectral analyzer (OSA)
  KU has developed a patented method of incorporating a Fabry Perot filter with a dispersive grating that provides high-resolution spectrum analysis over a wide optical bandwidth.
• Histology CD ROM
  Histology CD ROM containing over 300 images.
• Hsp90 inhibitors
  The molecules identified herein are designed to inhibit Hsp90 and thus prevent the conformational maturation of Hsp90 dependent proteins.
• Human herpes virus-6 monoclonal antibodies and proteins
  Monoclonal antibodies.
• Infrastructure protection from biological and chemical attacks by incineration with a regenerative heat exchanger
  This invention is a new use for a regenerative heat exchangers in general, and the Cotrell-type regenerative heat exchanger.
• Infectious DNA as a vaccine against West Nile and other flaviviruses
  West Nile Virus vaccine.
• Invasive species predictive software
  The procedures represent a new process in predicting, analyzing, and strategizing for combat of species invasions. It uses a novel combination of tools drawn from the emerging field of biodiversity.
• Iridium-based data communication system
  This technology uses multilink point-to-point protocol (MLPPP) over the Iridium satellite system to provide access to the internet from all over the world.
• Iron assay to measure total iron content in biological fluids, tissues and other specimens
  The assay will measure total iron in biological fluids (cerebral spinal fluid, serum, urine), tissues, and soils.
• KeyConcept (Conceptual Search Engine)
  This search engine retrieves documents based upon a combination of keywords and conceptual matching. Documents are automatically classified to determine the concepts to which they belong.
• KU RFID tag
  The KU RFID tag is an EPC-compliant UHF RFID tag that has a thin profile, small form factor and is capable of high performance when mounted on or near metal or liquid surfaces.
• Lossy substrate to emulate resistor-loaded microstrip antenna for passive UHF RFID tags
  Use of a resistor chip-loaded microstrip has been established as a way to make a microstrip antenna have larger bandwidth.
• Lysine-spermine conjugates: Hydrophobic polyamine amides as potent Lipopolysaccharide sequestrants
  The invention is the use of lysine-spermine conjugates in the treatment of sepsis.
• MALDI TOF mass spectrometry-based amino acid analysis
  A MALDI TOF-based method for the quantitative analysis of amino acids.
• Manufacturing technique for passive RFID tags with shorted microstrip antennas
  A microstrip RFID tag is comprised of an antenna, matching circuit, integrated circuit(IC), substrate, and ground plane.
• Manufacturing technique for passive RFID tags with microstrip antennas
  A microstrip WID tag is comprised of an antenna, matching circuit, integrated circuit (IC), substrate, and ground plane.
• Method for collection, storage and activation of immotile sperm
  A method, which increases the longevity of sperm for a number of species.
• Method of conducting an endothermic reaction in a packed-bed reactor with external energy addition
  For solid-catalyzed exothermic reactions in packed-bed reactors, it has been established that periodic reverse flow operation can significantly reduce energy requirements as compared to conventional operation using unidirectional flow.
• Methods for producing nanoparticulate metal complexes with compressed carbon dioxide: Correlation of particle morphology with precursor structure
  Method for production of nanoparticles.
• Method for the production of purified invasin protein and use thereof
  Vaccine Adjuvant.
• Microstrip RFID tags using virtual short circuit
  A microstrip RFID tag is comprised of an antenna, matching circuit, integrated circuit (IC), substrate, and ground plane.
• Novel acylspermines as sequestrants of bacterial endotoxins
  A novel class of compounds that bind and neutralize bacterial endotoxins.
• Novel compounds for male contraception
  Researchers have begun investigating compounds which inhibit spermatogenesis by disrupting junctional complex sites between Sertoli cells and germ cells in the testes.
• Novel compound for the treatment of sepsis and septic shock
  Simple synthetic compounds of low toxicity have been identified for the treatment of sepsis and shock.
• Novel gene therapy for treating prostate cancer
  Using RNAi technique, researchers at the University of Kansas Medical Center have been able to target AR protein expression in prostate cancer cells and develop novel therapeutic strategies.
• Novel protein folding system
  An in vitro protein folding system for preventing large scale protein misfolding and aggregation and for concentrating aggregation prone in a stable non-aggregation form.
• Novel strategies to enhance effectiveness and targeting of drugs in cells
  The invention represents a novel idea for regulating the activity of drugs through rational manipulation of their intracellular localization within a cell.
• Novobiocin analogues as anticancer agents
  Novobiocin has previously been shown to be an inhibitor of Hsp90. In an effort to produce more effective inhibitors of Hsp90, analogues of novobiocin have been prepared.
• NTrainer System™
  NTrainer System™ employs an electronic pacifier to assess and then improve a newborn baby’s essential oromotor skills, such as sucking and pre-feeding skills.
• Phase-change structural insulated panel
  This structural wall panel for building applications provides a lightweight, high strength, insulated panel, which is easily fabricated, modified and installed.
• Photoactivated agent for bonding tissue containing Type-I collagen
  A preliminary step in designing and synthesizing photoactivated compounds that could potentially be used as an alternative to sutures or staples in surgical wound closure of collagenous tissues.
• Plume Busters
  The prototype Plume Busters is a potentially Web-based, interactive educational software in which students use their knowledge of ground-water flow principles and contaminant transport.
• Polyclonal antibodies to prolactin and placental proteins
  Rabbit polyclonal antibodies.
• Portable device for measuring stroke symptoms
  A unique portable device that records time-series measurement of major stroke symptoms.
• Potent CXCR4 chemokine receptor antagonists
  The invention is a composition of matter consisting of synthetic peptides. To our knowledge, these peptides have the highest CXCR4 receptor antagonist activity reported.
• Preclinical model of simultaneous breast and ovarian cancer in a rat
  A method has been developed for rat models which have been treated simultaneously with carcinogenic agents to both the ovary and mammary glands.
• Production of micron and submicron composite particles
  The invention is a new process to prepare micron and submicron size particles of selected agents.
• Quantitative analysis of cytochrome P450 isozymes by means of unique isozyme-specific tryptic peptides: A proteomic approach combining mass spectrometry and immunochemistry
  A method developed capable to quantitate human cytochromes P450 in in vivosamples.
• Quarked Project
  Cartoon characters, a web and television format presentations, and facilitated show presentations for use in educating kids about science.
• Recombinant soluble HLA-G molecules
  A genetic strategy for producing unlimited quantities of pure recombinant HLA-G proteins, including soluble HLA-G1 and soluble HLA-G2.
• Shallow feature selection
  This computational algorithm for feature selection and classification can be applied to microarray data to extract genes related to some specific biological mechanism.
• Shorted microstrip antenna design for passive RFID tags
  A microstrip RFID tag is comprised of an antenna, matching circuit, integrated circuit (IC), substrate, and ground plane.
• SmartXAutofill
  SmartXAutofill is an intelligent assistant that automates data entry for XML documents by predicting the values of XML fields.
• Split bit
  The split bit is a wedging device that replaces steel plates, expendable points, and solid pilot bits. The split bit is removable and thereby leaves no foreign objects in the formation.
• Stroke Impact Scale (SIS)
  Created to assess changes in impairments, disabilities and handicaps following a stroke.
• Super Quik-Gene Kit
  The Super Quik-Gene kit has the capability of extracting high quality DNA from large quantities (100 to 8.5 mls.) of anti-coagulated whole blood samples or fibroblast tissue cultures.
• Synthesis of new analogues of lonidamine and their use as a antispermatogenic male contraceptive
  Composition of matter for new analogues of lonidamine and their synthesis by a new process and improved method for male contraception being non-hormonal, non-steroidal, and reversible.
• Temporal Search Engine
  The Temporal Search Engine tracks changes to documents on the Web over time, maintains a history of document versions and highlights changes to subsequent versions of each document.
• Thin film Hg-based superconductors, thermoelectric materials and methods of fabrication thereof
  This is a new process for fabrication of high-quality epitaxial Hg-based superconducting films; neither the degree of epitaxy nor the level of Jc have been achieved previously.
• Ultrasound elasticity imaging
  A new method and a corresponding system for estimating tissue elasticity using ultrasound.
• Unique mouse model bearing a tissue-specific targeting and temporal controllable AKT kinase activation system
  A transgenic mouse model has been created where the inactive form of Akt kinase can be activated or inactivated in order to study its function virtually in any tissue or organ.
• Versatile method for estimating the number of viable cells in multi-well culture
  A homogeneous tetrazolium-reduction assay for determining the number of living cells in multi-well culture has been designed and its reagents are available as a 2-part kit.
• Water soluble prodrugs of hindered alcohols and phenols
  Using prodrugs to lower pain and harmful side effects for drugs with poor water soluability.
• XREM-SPAP reporter gene and a validated 96-well plate assay for use in the identification of novel PXR ligands
  The invention described here is a novel reporter gene (plasmid) that is transactivated by the pregnane X receptor (PXR) transcription factor in the presence of PXR activators.